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May 13, 2010

Vitamin A of maternal affect offspring's lung function

LONDON: Scientists 've discovered that deficiency of Vitamin A in the mother's body may affect the lung function in the child.
Scientists at The Johns Hopkins Bloomberg School of Public Health conducted a study in order to come to this conclusion.
"Children of mothers who received Vitamin A supplementation before, during & after pregnancy had significantly improved lung function when compared to those whose mothers received beta-carotene supplementation or placebo," said lead author of the study, William Checkley, MD, PhD, assistant professor in the Division of Pulmonary & Critical Care of the Johns Hopkins School of Medicine with a joint appointment in the Bloomberg School's Department of International Health.

They found that children whose mothers received Vitamin A instead of a placebo had a significantly greater forced expiratory volume at one second (FEV1) & a greater forced vital capacity (FVC), while children whose mothers received beta-carotene instead of a placebo had similar FEV & FVC.

Vitamin A deficiency affects nearly 190 million preschool-age children worldwide & is the underlying cause of 650,000 early childhood deaths annually. In the 1970s, Alfred Sommer, MD, MHS, dean emeritus at the Bloomberg School of Public Health, & colleagues discovered the link between Vitamin A deficiency & night blindness among children in rural Indonesia & found that Vitamin A given twice a year reduced childhood mortality by a third. The World Bank declared Vitamin A supplementation as one of the most cost-effective medical interventions of all time.
The results are published in the May 13, 2010, issue of the New England Journal of Medicine.

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